Incidental Gallbladder Carcinoma in Gallbladder Polyps: Challenges of Gallbladder Malignancy for an Endemic Population.
Incidental Gallbladder Carcinoma in Gallbladder Polyps: Challenges of Gallbladder Malignancy for an Endemic Population.
复制标题
胆囊息肉并发胆囊癌：胆囊切除术对地方病人群的挑战。
DOI：
10.21315/mjms2021.28.1.4
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发表时间：
2021-03
期刊：
影响因子：
--
通讯作者：
Saini V
中科院分区：
文献类型：
--
作者：
Gautam A;Pandey A;Masood S;Chauhan S;Choudhary D;Kumar S;Madhawan S;Jha S;Saini V
胆囊息肉是胆囊癌的癌前病变。这项研究旨在强调早期胆囊切除术在治疗地方性人群中的胆囊息肉中的作用。对印度北部一家三级转诊中心外科消化内科实施的2,076例LAP手术进行了回顾性分析，并分析了胆囊息肉的偶发恶性病变。采用第8版美国肿瘤联合委员会胆囊癌的肿瘤-淋巴结-转移(TNM)分期。54例胆囊息肉中，53例为良性组织学改变，1例固有层有恶性细胞，提示为T1a腺癌。恶性息肉患者年龄(57岁)高于非肿瘤患者，平均年龄为45岁(P=0.039)。恶性息肉的大小约为4 mm，显著小于良性息肉的平均大小7.9mm(P=0.031)。在处理小尺寸的胆囊息肉时，尤其是在胆囊癌的高发区，需要及早考虑进行胆囊切除术。
Gallbladder polyps are considered pre-malignant lesions of gallbladder carcinoma. This study aims to highlight the role of early cholecystectomy in the management of gallbladder polyps in an endemic population. A retrospective analysis of 2,076 lap cholecystectomy procedures performed at the Department of Surgical Gastroenterology at a tertiary referral centre in Northern India was conducted and incidental malignancy in gallbladder polyps analysed. The 8th edition of the American Joint Committee on Cancer for tumour-node-metastasis (TNM) staging of gallbladder carcinoma was used. Of 54 patients with gallbladder polyps, 53 had benign histology and one had malignant cells in the lamina propria suggestive of T1a adenocarcinoma. The patient with the malignant polyp was older (57 years old) than the patients in the non-cancer group, which had a mean age of 45 (P = 0.039). The size of the malignant polyp was approximately 4 mm, significantly smaller than the average 7.9 mm size of the benign polys (P = 0.031). Cholecystectomy needs to be considered early in the management of small-sized gallbladder polyps, particularly in areas endemic for gallbladder carcinoma.
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DOI：
10.1111/j.1440-1746.2005.03576.x
发表时间：
2005-02-01
影响因子：
4.1
作者：
Batra, Y;Pal, S;Tandon, RK
通讯作者：
Tandon, RK
影响因子：
0.4
作者：
Bansal, Virinder Kumar;Misra, Mahesh C.;Kapoor, V. K.
通讯作者：
Kapoor, V. K.
影响因子：
3.8
作者：
Aldouri, A. Q.;Malik, H. Z.;Toogood, G. J.
通讯作者：
Toogood, G. J.
影响因子：
4.5
作者：
Kwon, Wooil;Jang, Jin-Young;Kim, Sun-Whe
通讯作者：
Kim, Sun-Whe
影响因子：
5.9
作者：
Wiles R;Thoeni RF;Barbu ST;Vashist YK;Rafaelsen SR;Dewhurst C;Arvanitakis M;Lahaye M;Soltes M;Perinel J;Roberts SA
通讯作者：
Roberts SA