Sequences essential for activity of the thyroid hormone responsive transcription stimulatory element of the rat growth hormone gene.
Sequences essential for activity of the thyroid hormone responsive transcription stimulatory element of the rat growth hormone gene.
复制标题
对于大鼠生长激素基因的甲状腺激素反应性转录刺激元件的活性至关重要的序列。
作者:
P. Wight;M. Crew;S. Spindler
Thyroid hormone dependent transcription stimulatory and inhibitory elements exist at the 5'-end of the rat GH (rGH) gene (TSE and TIE, respectively). In this study, the location of the sequences essential for TSE activity was examined using stably transfected GC cells. Because the TIE may influence TSE activity, we investigated TSE activity both on the rGH promoter, in the presence of the TIE, and on the viral thymidine kinase promoter, with the TIE deleted. The results of these studies indicate that the minimum sequences essential for TSE activity exist between positions -194 and -169 of the rGH gene.
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DOI:
--
发表时间:
1986
期刊:
The Journal of biological chemistry
影响因子:
--
作者:
Wynshaw-Boris,A;Short,JM;Loose,DS;Hanson,RW
通讯作者:
Hanson,RW
DOI:
--
发表时间:
1984
期刊:
The Journal of biological chemistry
影响因子:
--
作者:
Jump,DB;Narayan,P;Towle,H;Oppenheimer,JH
通讯作者:
Oppenheimer,JH
DOI:
10.1126/science.3006253
发表时间:
1986
期刊:
Science (New York, N.Y.)
影响因子:
--
作者:
Scholer,H;Haslinger,A;Heguy,A;Holtgreve,H;Karin,M
通讯作者:
Karin,M
DOI:
10.1073/pnas.78.8.4733
发表时间:
1981-01-01
期刊:
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES
影响因子:
--
作者:
SEELIG, S;LIAW, C;OPPENHEIMER, JH
通讯作者:
OPPENHEIMER, JH
DOI:
--
发表时间:
1987
期刊:
The Journal of biological chemistry
影响因子:
--
作者:
Magnuson,MA;Quinn,PG;Granner,DK
通讯作者:
Granner,DK