Modern humans did not admix with Neanderthals during their range expansion into Europe.
Modern humans did not admix with Neanderthals during their range expansion into Europe.
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DOI：
10.1371/journal.pbio.0020421
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发表时间：
2004-12
期刊：
影响因子：
9.8
通讯作者：
Excoffier L
中科院分区：
文献类型：
--
作者：
Currat M;Excoffier L
尼安德特人在42,000到30,000年前被现代人取代的过程仍然耐人寻味。尽管迄今在数千名欧洲人和7名早期现代欧洲人中没有发现尼安德特人线粒体DNA(MtDNA)谱系，但不能排除这两个亚种之间高达25%的杂交比率。在这项研究中，我们引入了一个现实的模型，描述了早期现代人进入欧洲的范围扩大，以及他们与当地尼安德特人的竞争和潜在的混血。在这种情况下，明确地模拟尼安德特人的更替动态，我们估计两个种群之间的最大混交率应该小于0.1%。我们确实表明，欧洲尼安德特人mtDNA序列的缺失与两个群体之间最多120个混血事件是相容的，尽管他们的同居时间可能超过12,000年。这个极低的数字强烈表明尼安德特人女性和现代人类男性之间几乎完全不育，这意味着这两个群体可能是不同的生物物种。一个人类扩展到欧洲的模型显示，尼安德特人的女性和现代人的男性之间几乎完全不育，这意味着这两个群体可能是不同的生物物种。
The process by which the Neanderthals were replaced by modern humans between 42,000 and 30,000 before present is still intriguing. Although no Neanderthal mitochondrial DNA (mtDNA) lineage is found to date among several thousands of Europeans and in seven early modern Europeans, interbreeding rates as high as 25% could not be excluded between the two subspecies. In this study, we introduce a realistic model of the range expansion of early modern humans into Europe, and of their competition and potential admixture with local Neanderthals. Under this scenario, which explicitly models the dynamics of Neanderthals' replacement, we estimate that maximum interbreeding rates between the two populations should have been smaller than 0.1%. We indeed show that the absence of Neanderthal mtDNA sequences in Europe is compatible with at most 120 admixture events between the two populations despite a likely cohabitation time of more than 12,000 y. This extremely low number strongly suggests an almost complete sterility between Neanderthal females and modern human males, implying that the two populations were probably distinct biological species. A model of human expansion into Europe reveals almost complete sterility between Neanderthal females and modern human males, implying that the two populations were probably distinct biological species
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影响因子：
2.4
作者：
BERNATCHEZ, L;GLEMET, H;DANZMANN, RG
通讯作者：
DANZMANN, RG
DOI：
10.1046/j.1471-8286.2003.00582.x
发表时间：
2004-03-01
期刊：
MOLECULAR ECOLOGY NOTES
影响因子：
--
作者：
Currat, M;Ray, N;Excoffier, L
通讯作者：
Excoffier, L
影响因子：
10.7
作者：
Dupanloup, I;Bertorelle, G;Barbujani, G
通讯作者：
Barbujani, G
影响因子：
64.8
作者：
Hublin, JJ;Spoor, F;Condemi, S
通讯作者：
Condemi, S
DOI：
10.1111/j.1469-1809.1937.tb02153.x
发表时间：
1937-06-01
期刊：
ANNALS OF EUGENICS
影响因子：
--
作者：
Fisher, RA
通讯作者：
Fisher, RA