Magnetoencephalography detection of high-frequency oscillations in the developing brain.
Magnetoencephalography detection of high-frequency oscillations in the developing brain.
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DOI：
10.3389/fnhum.2014.00969
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发表时间：
2014
影响因子：
2.9
通讯作者：
Wang X
中科院分区：
文献类型：
--
作者：
Leiken K;Xiang J;Zhang F;Shi J;Tang L;Liu H;Wang X
Increasing evidence from invasive intracranial recordings suggests that the matured brain generates both physiological and pathological high-frequency signals. The present study was designed to detect high-frequency brain signals in the developing brain using newly developed magnetoencephalography (MEG) methods. Twenty healthy children were studied with a high-sampling rate MEG system. Functional high-frequency brain signals were evoked by electrical stimulation applied to the index fingers. To determine if the high-frequency neuromagnetic signals are true brain responses in high-frequency range, we analyzed the MEG data using the conventional averaging as well as newly developed time-frequency analysis along with beamforming. The data of healthy children showed that very high-frequency brain signals (>1000 Hz) in the somatosensory cortex in the developing brain could be detected and localized using MEG. The amplitude of very high-frequency brain signals was significantly weaker than that of the low-frequency brain signals. Very high-frequency brain signals showed a much earlier latency than those of a low-frequency. Magnetic source imaging (MSI) revealed that a portion of the high-frequency signals was from the somatosensory cortex, another portion of the high-frequency signals was probably from the thalamus. Our results provide evidence that the developing brain generates high-frequency signals that can be detected with the non-invasive technique of MEG. MEG detection of high-frequency brain signals may open a new window for the study of developing brain function.
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影响因子：
3
作者：
Kotecha, Rupesh;Xiang, Jing;deGrauw, Ton
通讯作者：
deGrauw, Ton
DOI：
10.1016/s0168-5597(98)00032-x
发表时间：
1998-11-01
期刊：
EVOKED POTENTIALS-ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY
影响因子：
--
作者：
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通讯作者：
Hashimoto, I
影响因子：
5.7
作者：
Ghuman, Avniel Singh;McDaniel, Jonathan R.;Martin, Alex
通讯作者：
Martin, Alex
影响因子：
2.4
作者：
Sakura, Yuji;Terada, Kiyohito;Inoue, Yushi
通讯作者：
Inoue, Yushi
影响因子：
4.6
作者：
Mosher, JC;Leahy, RM
通讯作者：
Leahy, RM