The Role of RP105 in Cardiovascular Disease through Regulating TLR4 and PI3K Signaling Pathways
The Role of RP105 in Cardiovascular Disease through Regulating TLR4 and PI3K Signaling Pathways
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RP105 通过调节 TLR4 和 PI3K 信号通路在心血管疾病中的作用
DOI:
10.1007/s11596-019-2017-3
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发表时间:
2019-04
影响因子:
2.4
通讯作者:
Zhi-xing FAN
中科院分区:
文献类型:
--
作者:
Jian YANG;Ping ZENG;Jun YANG;Zhi-xing FAN
Raidoprotective 105 (RP105) was first discovered on the surface of mouse B cells and it has been demonstrated that RP105 can function as an inflammatory regulator in cardiovascular disease (CVD), such as myocardial ischemic reperfusion injury (MI/RI), atherosclerosis and myocardial infarction (MI). As a member of Toll-like receptor (TLR) homolog which is capable of regulating toll-like receptor (TLR4) signaling pathway, RP105 is implicated in various biological processes. Mounting evidence suggests that RP105 regulates the function of TLR4 and phosphoinositide 3-kinase (PI3K) signaling pathways. Here, we review the effect of RP105 on CVD through regulating TLR4/PI3K signaling pathways.
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影响因子:
3.5
作者:
Chaojun Yang;Jun Yang;Jian Yang;Z. Fan
通讯作者:
Chaojun Yang;Jun Yang;Jian Yang;Z. Fan
影响因子:
5.3
作者:
A. Wezel;D. van der Velden;J. M. Maassen;H. M. Lagraauw;M. D. de Vries;J. Karper;J. Kuiper;I. Bot;P. Quax
通讯作者:
A. Wezel;D. van der Velden;J. M. Maassen;H. M. Lagraauw;M. D. de Vries;J. Karper;J. Kuiper;I. Bot;P. Quax
影响因子:
15.9
作者:
Frantz, S;Kobzik, L;Kelly, RA
通讯作者:
Kelly, RA
DOI:
--
发表时间:
2013
期刊:
--
影响因子:
--
作者:
A. Bastiaansen;M. Ewing;H. D. Boer;Tineke C. van der;Pouw Kraan;M. D. Vries;Erna A. B. Peters;Sabine M. J. Welten;Ramon;Arens;S. Moore;J. Faber;J. Jukema;J. Hamming;-A.;Y. Nossent;P. Quax
通讯作者:
A. Bastiaansen;M. Ewing;H. D. Boer;Tineke C. van der;Pouw Kraan;M. D. Vries;Erna A. B. Peters;Sabine M. J. Welten;Ramon;Arens;S. Moore;J. Faber;J. Jukema;J. Hamming;-A.;Y. Nossent;P. Quax
影响因子:
10.8
作者:
Ha, Tuanzhu;Hua, Fang;Li, Chuanfu
通讯作者:
Li, Chuanfu