Reliability of intra-oral quantitative sensory testing (QST) in patients with atypical odontalgia and healthy controls - a multicentre study.

Reliability of intra-oral quantitative sensory testing (QST) in patients with atypical odontalgia and healthy controls - a multicentre study.
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DOI:
10.1111/joor.12245
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发表时间:
2015-02
影响因子:
2.9
通讯作者:
Drangsholt M
Drangsholt M
中科院分区:
医学2区
文献类型:
--
作者:
Baad-Hansen L;Pigg M;Yang G;List T;Svensson P;Drangsholt M

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综合口腔内定量感觉测试(QST)方案在慢性口面部疼痛患者中的可靠性尚未得到系统的检验。这项多中心研究的目的是检查口腔内QST测量的绝对值和z分数以及会话内变异系数(CV)值在非典型牙痛患者和健康无痛对照组中的重测和检查者间的可靠性。对45例AO患者和68例健康对照进行了三次口腔内QST和单侧三叉神经外QST(大鱼际)检查(一天两次,约一周后由其中一位检查者进行一次)。计算了检验员间信度和重测信度的组内相关系数和kappa值。大多数标准化的口腔内QST测量显示出中等到优秀的检查者间(13个测量中的9-12个)和重测(13个测量中的7-11个)的可靠性。此外,在AO患者和健康参照组之间,在可靠性测量或会话内变异性(CV)方面没有发现显著差异。这些在慢性口面部疼痛患者中的可靠性结果支持了基于健康受试者数据的早期建议,即口腔内QST足够可靠,可以作为三叉神经区躯体感觉障碍或神经性疼痛患者综合评估的一部分。
The reliability of comprehensive intraoral quantitative sensory testing (QST) protocol has not been examined systematically in patients with chronic orofacial pain. The aim of the present multi-center study was to examine test-retest and inter-examiner reliability of intraoral QST measures in terms of absolute values and z-scores as well as within-session coefficients of variation (CV) values in patients with atypical odontalgia (AO) and healthy pain-free controls. Forty-five AO patients and 68 healthy controls were subjected to bilateral intraoral gingival QST and unilateral extratrigeminal QST (thenar) on three occasions (twice on one day by two different examiners and once approximately one week later by one of the examiners). Intraclass correlation coefficients and kappa values for inter-examiner and test-retest reliability were computed. Most of the standardized intraoral QST measures showed fair to excellent inter-examiner (9–12 of 13 measures) and test-retest (7–11 of 13 measures) reliability. Furthermore, no robust differences in reliability measures or within-session variability (CV) were detected between AO patients and the healthy reference group. These reliability results in chronic orofacial pain patients support earlier suggestions based on data from healthy subjects that intraoral QST is sufficiently reliable for use as a part of a comprehensive evaluation of patients with somatosensory disturbances or neuropathic pain in the trigeminal region.
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