Bibliometric and visual analysis of blood-testis barrier research.
Bibliometric and visual analysis of blood-testis barrier research.
复制标题
血睾屏障研究的文献计量和可视化分析。
DOI：
10.3389/fphar.2022.969257
复制
发表时间：
2022
影响因子：
5.6
通讯作者：
Chang, Degui
中科院分区：
文献类型：
--
作者：
Shen, Yifeng;You, Yaodong;Zhu, Kun;Fang, Chunyan;Yu, Xujun;Chang, Degui
背景：近年来对血睾丸屏障进行了广泛的研究。然而，目前还没有对这一主题进行系统的文献计量研究。我们的研究旨在确定血睾丸屏障研究的热点和前沿，为未来该领域的科学研究和决策提供指导。方法：在Web of Science核心馆藏中找到有关血睾丸屏障的研究。使用VOSviewer、CiteSpace和Microsoft Excel进行文献计量学和可视化分析。结果：我们在1992年至2022年间发现了942篇用英语发表的血睾丸屏障研究。2011年至2022年间，年度出版物和引用数量显著增加，尤其是在美国。中国和美国、美国人口委员会、内分泌学和程春燕分别是产出最多的国家、机构、期刊和作者。研究关键词表明，血睾丸屏障研究涉及多种组成特征（紧密连接、细胞骨架、粘附连接）、细胞类型（支持细胞、生殖细胞、间质细胞、干细胞）、生殖毒性（镉、纳米颗粒、双酚a）以及相关机制（精子发生、凋亡、氧化应激、动力学、炎症、免疫特权）。结论：男性不育症患者血睾丸屏障的组成和分子过程以及血睾丸屏障的研究是该领域的主要研究热点。此外，未来的研究可能会集中在治疗和开发新的药物，以氧化应激和细胞凋亡的信号通路为目标，以保护血睾丸屏障。进一步的研究必须扩展到临床诊断和治疗。
Background: Extensive research on the blood-testis barrier has been undertaken in recent years. However, no systematic bibliometric study has been conducted on this subject. Our research aimed to identify the hotspots and frontiers of blood-testis barrier research and to serve as a guide for future scientific research and decision-making in the field. Methods: Studies on the blood-testis barrier were found in the Web of Science Core Collection. VOSviewer, CiteSpace, and Microsoft Excel were used to conduct the bibliometric and visual analyses. Results: We found 942 blood-testis barrier studies published in English between 1992 and 2022. The number of annual publications and citations increased significantly between 2011 and 2022, notably in the United States. China and the United States, the US Population Council, Endocrinology, and Cheng C. Yan were the most productive countries, institution, journal, and author, respectively. The study keywords indicated that blood-testis barrier research involves a variety of compositional features (tight junctions, cytoskeleton, adherens junctions), cell types (Sertoli cells, germ cells, Leydig cells, stem cells), reproductive toxicity (cadmium, nanoparticles, bisphenol-a), and relevant mechanisms (spermatogenesis, apoptosis, oxidative stress, dynamics, inflammation, immune privilege). Conclusion: The composition and molecular processes of the blood-testis barrier as well as the blood-testis barrier in male infertility patients are the primary research hotspots in this field. In addition, future research will likely focus on treatment and the development of novel medications that target signal pathways in oxidative stress and apoptosis to preserve the blood-testis barrier. Further studies must extend to clinical diagnosis and therapy.
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DOI：
10.1038/nrendo.2010.71
发表时间：
2010-07
期刊：
Nature reviews. Endocrinology
影响因子：
--
作者：
通讯作者：
--
影响因子：
4.4
作者：
Dominguez-Salazar, Emilio;Hurtado-Alvarado, Gabriela;Gomez-Gonzalez, Beatriz
通讯作者：
Gomez-Gonzalez, Beatriz
影响因子：
8.8
作者：
Chen, Yixia;Lin, Mingwei;Zhuang, Dan
通讯作者：
Zhuang, Dan
影响因子：
2.8
作者：
Gurel, Cevik;Kuscu, Gokce Ceren;Yavasoglu, Altug
通讯作者：
Yavasoglu, Altug
影响因子：
2.9
作者：
Ha, Hong Koo;Park, Hyun Jun;Park, Nam Cheol
通讯作者：
Park, Nam Cheol