Pattern-reversal electroretinograms in unilateral glaucoma.

Pattern-reversal electroretinograms in unilateral glaucoma.
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单侧青光眼的模式反转视网膜电图。

DOI:
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发表时间:
1983
影响因子:
4.4
通讯作者:
H. Persson
H. Persson
中科院分区:
医学2区
文献类型:
--
作者:
P. Wanger;H. Persson

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记录了 11 名单侧青光眼患者的模式反转、闪光视网膜电图 (ERG) 和振荡电位 (OP)。与同一患者的另一只眼睛和参考值相比,所有青光眼眼睛的振幅均降低。在这 11 个案例中,有 10 个案例的这种减少低于正常变异水平。青光眼眼和对侧眼的模式反转 ERG 振幅平均值差异具有统计学显着性。在闪光 ERG 或 OP 中没有观察到差异。与青光眼视野缺陷相关的组织病理学是视网膜神经节细胞变性。目前的电生理学研究结果支持基于动物实验结果的观点,即模式反转 ERG 反映了神经节细胞的活动。
Pattern-reversal and flash electroretinograms (ERG) and oscillatory potentials (OP) were recorded from 11 patients with unilateral glaucoma. All glaucomatous eyes had reduced amplitudes both compared to the opposite eye in the same patient and to reference values. In 10 of the 11 cases this reduction was below the level of normal variation. The difference in pattern-reversal ERG amplitude means from glaucomatous and opposite eyes was statistically significant. No differences were observed in flash ERGs or OPs. The histopathologic correlate to the visual field defects in glaucoma is retinal ganglion cell degeneration. The present electrophysiologic findings support the view, based on results from animal experiments, that the pattern-reversal ERG reflects ganglion cell activity.
DOI: 10.1001/archopht.1981.03930010635009
发表时间: 1981-01-01
影响因子: --
作者:
QUIGLEY, HA;ADDICKS, EM;MAUMENEE, AE
通讯作者: MAUMENEE, AE