Socioeconomic disadvantage, fetal environment and child development: linked Scottish administrative records based study.
Socioeconomic disadvantage, fetal environment and child development: linked Scottish administrative records based study.
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DOI：
10.1186/s12939-017-0698-4
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发表时间：
2017-11-22
影响因子：
4.8
通讯作者：
Williamson L
中科院分区：
文献类型：
--
作者：
Playford CJ;Dibben C;Williamson L
儿童期的认知发展受到社会经济不利因素的负面影响。本研究探讨了胎儿环境的差异是否可能介导家庭社会经济地位和儿童发育之间的关联。数据来自苏格兰纵向研究、产妇住院记录和儿童健康监测方案-32,238名儿童的学前教育。结果变量基于健康访视者对大运动、听力和语言、视力和精细运动以及社会发展的评估。社会经济地位是用父母的社会阶层和获得的最高资格来衡量的。估计随机效应逻辑回归模型，以解释多个审查和家族聚集。中介分析采用Karlson-Holm-Breen方法。在调整胎儿环境后，听力和语言、视力和精细运动以及社会发育与父母社会阶层较低和父母教育资格较低有关。胎儿环境部分介导了父母没有教育资格对听力和语言（β = 0.15; 95%置信区间（CI）= 0.07，0.23），视力和精细运动（β = 0.19; CI = 0.10，0.28）和社会发展（β = 0.14; CI = 0.03至0.25）的估计影响。社会经济地位预测听力和语言，视力和精细运动，社会发展，但不大运动的发展。对于父母没有受过教育的孩子来说，胎儿环境似乎有助于儿童发育异常的社会经济梯度的一部分，但出生后环境似乎仍然可以解释大多数梯度，而对于其他孩子来说，大多数梯度。（10.1186/s12939-017-0698-4）包含授权用户可用的补充材料。
Cognitive development in childhood is negatively affected by socioeconomic disadvantage. This study examined whether differences in fetal environment might mediate the association between family socioeconomic position and child development. Data were linked from the Scottish Longitudinal Study, maternity inpatient records and the Child Health Surveillance Programme – Pre School for 32,238 children. The outcome variables were based on health visitor assessment of gross motor, hearing and language, vision and fine motor, and social development. Socioeconomic position was measured using parental social class and highest qualification attained. Random-effects logistic regression models were estimated to account for multiple reviews and familial clustering. Mediation analysis was conducted using the Karlson-Holm-Breen method. Hearing and language, vision and fine motor, and social development were associated with lower parental social class and lower parental educational qualifications after adjustment for fetal environment. Fetal environment partially mediated the estimated effect of having parents without educational qualifications for hearing and language (β = 0·15; 95% confidence interval (CI) = 0·07, 0·23), vision and fine motor (β = 0·19; CI = 0·10, 0·28) and social development (β = 0·14; CI = 0·03 to 0·25). Socioeconomic position predicted hearing and language, vision and fine motor, and social development but not gross motor development. For children of parents without educational qualifications, fetal environment appears to contribute to a part of the socioeconomic gradient in child development abnormalities but post-natal environment appears to still explain the majority of the gradient and for other children most of it. The online version of this article (10.1186/s12939-017-0698-4) contains supplementary material, which is available to authorized users.
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影响因子：
1.3
作者：
Olusanya, Bolajoko O.
通讯作者：
Olusanya, Bolajoko O.
影响因子：
4.4
作者：
Riordan, Daniel Vincent;Morris, Carole;Stark, Cameron
通讯作者：
Stark, Cameron
影响因子：
2.4
作者：
Blackburn CM;Spencer NJ;Read JM
通讯作者：
Read JM
影响因子：
3.1
作者：
Bonellie S;Chalmers J;Gray R;Greer I;Jarvis S;Williams C
通讯作者：
Williams C
影响因子：
6.3
作者：
Galobardes, B;Shaw, M;Smith, GD
通讯作者：
Smith, GD