Bibliometric Evaluation of 2012-2020 Publications on Ferroptosis in Cancer Treatment.
Bibliometric Evaluation of 2012-2020 Publications on Ferroptosis in Cancer Treatment.
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DOI：
10.3389/fcell.2021.793347
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发表时间：
2021
影响因子：
5.5
通讯作者：
Yang M
中科院分区：
文献类型：
--
作者：
Zhou Q;Wu F;Zhao M;Yang M
铁凋亡（Ferroptosis）是一种由脂质过氧化物积累引起的铁依赖性调节性细胞死亡，在形态和机制上不同于凋亡、自噬、坏死性凋亡等其他形式的调节性细胞死亡。近年来，它引起了世界各国学者的兴趣和关注。近年来的研究表明，铁凋亡在肿瘤治疗中发挥着重要作用，为肿瘤的靶向治疗提供了广阔的前景。本文旨在分析目前有关铁缺乏症在癌症治疗领域应用的科学成果，为进一步研究提供新的思路。我们从Web of Science Core Collection（WoSCC）中检索了2012年至2020年与铁凋亡和癌症治疗相关的出版物，并根据纳入标准进行筛选。共收录相关论文965篇，发表总数逐年上升。我们使用CiteSpace 5.7。使用R2、VOSviewer和Microsoft Excel 2019评估和可视化结果，分析机构、国家/地区、期刊、作者、共引参考文献和关键词。总体而言，随着越来越多的证据显示铁凋亡在癌症中不可或缺的作用，其机制研究和靶点发现可能成为未来研究的主要方向。
Ferroptosis is an iron-dependent regulated cell-death caused by the accumulation of lipid peroxides, which is different from apoptosis, autophagy, necroptosis and other forms of regulatory cell death in morphology and mechanism. It has attracted interest and attention of scholars from all over the world during the past years. Recent studies have shown that ferroptosis is able to play a clear and important role in cancer treatment, providing a bright prospect for targeted cancer therapy. This article aims to analyze current scientific results about the application of ferroptosis in the field of cancer treatment, providing new ideas for further research. We retrieved publications related to ferroptosis and cancer treatment from 2012 to 2020 from the Web of Science Core Collection (WoSCC), screening them according to the inclusion criteria. A total of 965 related papers were included, and the total number of publications increased year by year. We used CiteSpace 5.7. R2, VOSviewer and Microsoft Excel 2019 to evaluate and visualize the results, analyzing institutions, countries/regions, journals, authors, co-cited reference and keywords. Overall, with more and more evidence showing the indispensable role of ferroptosis in cancer, its mechanism research and target discovery may become the main direction of future research.
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肿瘤抑制蛋白 p53 和铁死亡网络
影响因子：
7.4
作者：
Kang R;Kroemer G;Tang D
通讯作者：
Tang D
影响因子：
64.5
作者：
Dixon SJ;Lemberg KM;Lamprecht MR;Skouta R;Zaitsev EM;Gleason CE;Patel DN;Bauer AJ;Cantley AM;Yang WS;Morrison B 3rd;Stockwell BR
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Stockwell BR
影响因子：
11.4
作者：
Roh, Jong-Lyel;Kim, Eun Hye;Jang, Hyejin;Shin, Daiha
通讯作者：
Shin, Daiha
DOI：
10.1107/s2059798320016125
发表时间：
2021-02-01
期刊：
Acta crystallographica. Section D, Structural biology
影响因子：
--
作者：
Moosmayer D;Hilpmann A;Hoffmann J;Schnirch L;Zimmermann K;Badock V;Furst L;Eaton JK;Viswanathan VS;Schreiber SL;Gradl S;Hillig RC
通讯作者：
Hillig RC
DOI：
10.1126/science.aaw9872
发表时间：
2020-04-03
期刊：
Science (New York, N.Y.)
影响因子：
--
作者：
Badgley MA;Kremer DM;Maurer HC;DelGiorno KE;Lee HJ;Purohit V;Sagalovskiy IR;Ma A;Kapilian J;Firl CEM;Decker AR;Sastra SA;Palermo CF;Andrade LR;Sajjakulnukit P;Zhang L;Tolstyka ZP;Hirschhorn T;Lamb C;Liu T;Gu W;Seeley ES;Stone E;Georgiou G;Manor U;Iuga A;Wahl GM;Stockwell BR;Lyssiotis CA;Olive KP
通讯作者：
Olive KP