Slow and fast γ rhythms coordinate different spatial coding modes in hippocampal place cells.
Slow and fast γ rhythms coordinate different spatial coding modes in hippocampal place cells.
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DOI:
10.1016/j.neuron.2014.03.013
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发表时间:
2014-05-07
期刊:
影响因子:
16.2
通讯作者:
Colgin LL
中科院分区:
文献类型:
--
作者:
Bieri KW;Bobbitt KN;Colgin LL
Previous work has hinted that prospective and retrospective coding modes exist in hippocampus. Prospective coding is believed to reflect memory retrieval processes, whereas retrospective coding is thought to be important for memory encoding. Here, we show in rats that separate prospective and retrospective modes exist in hippocampal subfield CA1 and that slow and fast gamma rhythms differentially coordinate place cells during the two modes. Slow gamma power and phase-locking of spikes increased during prospective coding; fast gamma power and phase-locking increased during retrospective coding. Additionally, slow gamma spikes occurred earlier in place fields than fast gamma spikes, and cell ensembles retrieved upcoming positions during slow gamma and encoded past positions during fast gamma. These results imply that alternating slow and fast gamma states allow the hippocampus to switch between prospective and retrospective modes, possibly to prevent interference between memory retrieval and encoding.
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影响因子:
16.2
作者:
Carr MF;Karlsson MP;Frank LM
通讯作者:
Frank LM
DOI:
10.1523/jneurosci.5110-11.2012
发表时间:
2012-05-23
期刊:
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子:
--
作者:
Ahmed OJ;Mehta MR
通讯作者:
Mehta MR
影响因子:
56.9
作者:
Fyhn, M;Molden, S;Moser, MB
通讯作者:
Moser, MB
影响因子:
16.2
作者:
Ekstrom, AD;Meltzer, J;Barnes, CA
通讯作者:
Barnes, CA
影响因子:
2.9
作者:
Hasselmo, ME;Bodelón, C;Wyble, BP
通讯作者:
Wyble, BP