Effects of alcohol on functional development of the auditory pathway in the brainstem of infants and chick embryos.
Effects of alcohol on functional development of the auditory pathway in the brainstem of infants and chick embryos.
复制标题
酒精对婴儿和鸡胚胎脑干听觉通路功能发育的影响。
DOI：
--
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发表时间：
1984
期刊：
影响因子：
--
通讯作者：
I. Hutchinson
中科院分区：
文献类型：
--
作者：
A. Pettigrew;I. Hutchinson
The effects of alcohol on the development of neural function in the auditory pathway of the brainstem have been examined in human neonates and chick embryos. Auditory brainstem evoked responses were recorded in six infants of mothers for whom there was evidence of alcohol abuse during pregnancy. In four of the infants, evoked responses were abnormal, with poorly defined, inconsistent peaks. Neurophysiological and histological studies were done on chick embryos which received a single dose of alcohol early incubation. In most surviving embryos the neuroanatomical arrangement of the auditory nuclei in the brainstem was normal. However, Golgi impregnation revealed abnormalities in the length and structure of the dendrites in nucleus laminaris. Electrically evoked neuronal activity revealed abnormalities of synaptic function and the distribution of nerve terminals. The results indicate that in infants and chick embryos the functional development of the auditory pathway in the brainstem is disrupted by exposure to alcohol. Such early changes in this sensory pathway may contribute to the behavioural and intellectual handicaps associated with the fetal alcohol syndrome.
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DOI：
10.1016/0034-5687(81)90091-8
发表时间：
1981-01-01
期刊：
RESPIRATION PHYSIOLOGY
影响因子：
--
作者：
METCALFE, J;MCCUTCHEON, IE;WELCH, JE
通讯作者：
WELCH, JE
产前和产后早期接触乙醇会永久改变大鼠海马体。
DOI：
10.1002/9780470720868.ch2
发表时间：
1984
期刊：
Ciba Foundation symposium
影响因子：
--
作者：
West,JR;Dewey,SL;Pierce,DR;BlackJr,AC
通讯作者：
BlackJr,AC
DOI：
10.1016/0013-4694(82)90137-7
发表时间：
1982-01-01
期刊：
ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY
影响因子：
--
作者：
MOLLER, AR;JANNETTA, PJ
通讯作者：
JANNETTA, PJ
影响因子：
56.9
作者：
PURVES, D;LICHTMAN, JW
通讯作者：
LICHTMAN, JW