Cardiac magnetic resonance feature tracking of the right ventricle in convalescent Kawasaki disease in a large single center.
Cardiac magnetic resonance feature tracking of the right ventricle in convalescent Kawasaki disease in a large single center.
复制标题
DOI：
10.1002/clc.23512
复制
发表时间：
2021-01
影响因子：
2.7
通讯作者：
He LL
中科院分区：
文献类型：
--
作者：
Yao Q;Hu XH;He LL
川崎病（KD）右心室收缩力的变化尚不清楚。我们的目的是确定右心室收缩功能障碍是否可以通过心脏磁共振（CMR）特征跟踪检测，并找到其与冠状动脉病变（动脉瘤，血栓形成和狭窄）的关联。测定了66例恢复期KD患者右室整体及基底、中段、心尖三个水平的收缩期心肌纵向、径向、周向峰值应变及应变率（RVSL、RVSR、RVSC、RVSRL、RVSRR、RVSRC）。共纳入20个对照组。与对照组进行比较，并与冠状动脉病变的KD亚组之间进行比较。KD组的RVSC（−10.575% vs. −10.760%）、RVSL（−18.150% vs. −18.712%）和RVSRC（−0.815/s vs. −0.924/s）略低，但差异无统计学意义。所有的应变和应变速率都在基底层最低。在亚组比较中，巨大冠状动脉瘤（CAA）组的RVSL和RVSRL较低;血栓形成组的RVSR（15.844% vs. 16.897%）、RVSRR（1.245/s vs. 1.322/s）和RVSRC（−0.715/s vs. −0.895/s）较低;狭窄组的RVSRL（−1.27/s vs. −1.503/s）较低。各亚组间比较均未达到显著性差异。从受试者工作特征曲线分析，RVSRL对KD合并巨大CAA和狭窄的鉴别能力更强。RVSRC对血栓的识别能力较强。恢复期KD患儿RV的应变率和应变率均较低。在持续冠状动脉病变的患者中更明显。
The changes in right ventricular (RV) contractility of Kawasaki disease (KD) still remain unclear. We aimed to determine whether RV systolic dysfunction can be detected by cardiac magnetic resonance (CMR) feature tracking and to find its association with coronary artery lesions (aneurysm, thrombosis and stenosis). Peak systolic myocardial longitudinal, radial and circumferential strain and the strain rate (RVSL, RVSR, RVSC, RVSRL, RVSRR and RVSRC) in the global RV and three levels (basal, middle and apical) were measured in 66 patients with convalescent KD. A total of 20 controls were included. Comparisons were made with controls and among KD subgroups divided with coronary artery lesions. RVSC (−10.575% vs. −10.760%), RVSL (−18.150% vs. −18.712%) and RVSRC (−0.815/s vs. −0.924/s) were slightly lower in KD group without significant difference. All the strain and strain rate presented lowest in the basal level. In subgroup comparison, lower RVSL and RVSRL were observed in the giant coronary artery aneurysm (CAA) group; RVSR (15.844% vs. 16.897%), RVSRR (1.245/s vs. 1.322/s) and RVSRC (−0.715/s vs. −0.895/s) were lower in thrombosed group; RVSRL (−1.27/s vs. −1.503/s) were lower in stenosis group. All the comparison in subgroups did not reach significant difference. From the analysis of receiver operating characteristic curve, RVSRL had a better ability to identify KD with giant CAA and stenosis. For the identification of thrombosis, RVSRC had a better ability. Lower strain and strain rates of RV were detected in convalescent KD. More pronounced in those with persisting coronary artery lesions.
登录
查看更多内容
影响因子：
3.5
作者：
Liu B;Dardeer AM;Moody WE;Edwards NC;Hudsmith LE;Steeds RP
通讯作者：
Steeds RP
影响因子：
6.4
作者：
McLeod, Kristin;Wall, Samuel;Haugaa, Kristina Hermann
通讯作者：
Haugaa, Kristina Hermann
DOI：
10.1186/s12968-016-0258-x
发表时间：
2016-06-16
期刊：
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
影响因子：
--
作者：
de Siqueira ME;Pozo E;Fernandes VR;Sengupta PP;Modesto K;Gupta SS;Barbeito-Caamaño C;Narula J;Fuster V;Caixeta A;Sanz J
通讯作者：
Sanz J
影响因子：
5.5
作者：
Liu, Feng;Zhang, Han;Lu, Xueli
通讯作者：
Lu, Xueli
DOI：
10.1152/ajpheart.00429.2011
发表时间：
2012-01-01
影响因子：
4.8
作者：
Ferferieva, V.;Van den Bergh, A.;D'hooge, J.
通讯作者：
D'hooge, J.