Advancing the ethics of paleogenomics.
Advancing the ethics of paleogenomics.
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DOI：
10.1126/science.aaq1131
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发表时间：
2018-04-27
期刊：
影响因子：
--
通讯作者：
Summer internship for INdigenous peoples in Genomics (SING) Consortium
中科院分区：
文献类型：
--
作者：
Bardill J;Bader AC;Garrison NA;Bolnick DA;Raff JA;Walker A;Malhi RS;Summer internship for INdigenous peoples in Genomics (SING) Consortium
最近的科学发展重新引起人们对土著人民、科学界、殖民政府和古代人类遗骸之间复杂关系的关注 (1,2)。在美国发现的祖先遗骸的 DNA 检测越来越多地被用于解决这些遗骸的争议 (3)。然而，古基因组学中的伦理原则和实践的阐述并没有跟上（4），即使这些研究的结果可能产生负面后果，破坏条约、遣返、领土或其他法律案件中的社区主张或使其复杂化。古基因组叙述也可能误解或与群落历史相矛盾，从而可能损害群落或个人身份。古基因组数据可以揭示有关可能造成耻辱的后代群落的信息，例如对疾病的遗传易感性。考虑到对土著社区的潜在后果，古基因组研究人员比过去更仔细地考虑他们的道德义务至关重要。
Recent scientific developments have drawn renewed attention to the complex relationships among Indigenous peoples, the scientific community, settler colonial governments, and ancient human remains (1,2). Increasingly, DNA testing of ancestral remains uncovered in the America s is being used in disputes over these remains (3). However, articulations of ethical principles and practices in paleogenomics have not kept pace (4), even as results of these studies can have negative consequences, undermining or complicating community claims in treaty, repatriation, territorial, or other legal cases. Paleogenomic narratives may also misconstrue or contradict community histories, potentially harming community or individual identities. Paleogenomic data can reveal information about descendant communities that may be stigmatizing, such as genetic susceptibilities to disease. Given the potential consequences for Indigenous communities, it is critical that paleogenomic researchers consider their ethical obligations more carefully than in the past.
影响因子：
16.6
作者：
Kennett DJ;Plog S;George RJ;Culleton BJ;Watson AS;Skoglund P;Rohland N;Mallick S;Stewardson K;Kistler L;LeBlanc SA;Whiteley PM;Reich D;Perry GH
通讯作者：
Perry GH
影响因子：
64.8
作者：
Rasmussen M;Sikora M;Albrechtsen A;Korneliussen TS;Moreno-Mayar JV;Poznik GD;Zollikofer CPE;de León MP;Allentoft ME;Moltke I;Jónsson H;Valdiosera C;Malhi RS;Orlando L;Bustamante CD;Stafford TW Jr;Meltzer DJ;Nielsen R;Willerslev E
通讯作者：
Willerslev E