Actions of vasodilator nerves on arteriolar smooth muscle and neurotransmitter release from sympathetic nerves in the guinea‐pig small intestine.

Actions of vasodilator nerves on arteriolar smooth muscle and neurotransmitter release from sympathetic nerves in the guinea‐pig small intestine.
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血管扩张神经对豚鼠小肠小动脉平滑肌和交感神经释放神经递质的作用。

DOI:
10.1113/jphysiol.1995.sp021097
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发表时间:
1995
期刊:
The Journal of Physiology
影响因子:
--
通讯作者:
T. Neild
T. Neild
中科院分区:
--
文献类型:
--
作者:
N. Kotecha;T. Neild

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1.通过刺激血管周围交感神经诱发豚鼠小肠离体粘膜下层的小动脉短暂收缩。粘膜下神经丛中血管扩张神经元的先前刺激大大降低了交感神经刺激的收缩反应。2.血管扩张神经刺激降低了交感神经刺激引起的小动脉平滑肌兴奋性连接电位(EJP)的幅度和衰减率。3.对EJP振幅的膜电阻变化的影响的计算机模拟表明,振幅的变化不能单独用膜电阻的下降来解释,这表明血管扩张神经活动减少了交感神经的神经递质释放。
1. Brief constrictions of arterioles of the isolated submucosa of the guinea‐pig small intestine were evoked by stimulation of the perivascular sympathetic nerves. Prior stimulation of vasodilator neurones in the submucosal nerve plexus greatly reduced the constrictor response to sympathetic stimulation. 2. Vasodilator nerve stimulation reduced both the amplitude and rate of decay of the excitatory junction potential (EJP) evoked in the arteriolar smooth muscle by sympathetic nerve stimulation. 3. Computer simulation of the effect of membrane resistance changes on the EJP amplitude indicated that the change in amplitude could not be explained by the fall in membrane resistance alone, suggesting that vasodilator nerve activity reduced neurotransmitter release from the sympathetic nerves.
粘膜刺激通过神经元和非神经元机制引起粘膜下小动脉的血管舒张。
DOI: 10.1152/ajpgi.1993.264.2.g202
发表时间: 1993
期刊: The American journal of physiology
影响因子: --
作者:
Vanner,S;Jiang,MM;Surprenant,A
通讯作者: Surprenant,A
豚鼠粘膜下丛中的霍乱毒素敏感神经元。
DOI: 10.1152/ajpgi.1993.264.1.g86
发表时间: 1993
期刊: The American journal of physiology
影响因子: --
作者:
Jiang,MM;Kirchgessner,A;Gershon,MD;Surprenant,A
通讯作者: Surprenant,A