Recipe for IBD: can we use food to control inflammatory bowel disease?

Recipe for IBD: can we use food to control inflammatory bowel disease?
复制标题

DOI:
10.1007/s00281-017-0658-5
复制
发表时间:
2018-03
影响因子:
9
通讯作者:
Huber S
Huber S
中科院分区:
医学1区
文献类型:
--
作者:
Witkowski M;Witkowski M;Gagliani N;Huber S

文献摘要

参考文献

被引文献

相似文献

肠道中的粘膜免疫系统和微生物群最近被证明在炎症性肠病(IBD)的发病机制中起关键作用。这两者都可能受到食物的影响。因此,我们建议饮食干预作为IBD的治疗选择。在这篇综述中,我们讨论了IBD背景下肠粘膜免疫系统和肠道微生物群的相互作用。此外,我们还讨论了食物成分对IBD免疫反应的影响。最后,我们解决了目前的证据,这种相互作用(即,免疫系统-微生物群)可以通过食物组分、益生元/益生菌和粪便微生物群移植(FMT)以及这些方法如何支持肠道稳态来调节。通过收集大量关于食物对IBD影响的文献,我们的目标是区分科学合理的数据和理论,这些数据和理论未被纳入本综述。
The mucosal immune system and the microbiota in the intestinal tract have recently been shown to play a key role in the pathogenesis of inflammatory bowel disease (IBD). Both of these can be influenced by food. Thus, we propose dietary intervention as a therapeutic option for IBD. In this review, we discuss the interaction of the intestinal mucosal immune system and the intestinal microbiota in the context of IBD. In addition, we discuss the impact of food components on immune responses in IBD. Finally, we address the current evidence of how this interaction (i.e., immune system–microbiota) can be modulated by food components, pre/probiotics, and fecal microbiota transplantation (FMT) and how these approaches can support intestinal homeostasis. By gathering the vast amount of literature available on the impact of food on IBD, we aim to distinguish between scientifically sound data and theories, which have not been included in this review.
DOI: 10.1186/s12967-015-0646-2
发表时间: 2015-09-12
影响因子: 7.4
作者:
Cui B;Li P;Xu L;Zhao Y;Wang H;Peng Z;Xu H;Xiang J;He Z;Zhang T;Nie Y;Wu K;Fan D;Ji G;Zhang F
通讯作者: Zhang F
DOI: 10.1038/nature11225
发表时间: 2012-07-05
期刊: NATURE
影响因子: 64.8
作者:
Devkota, Suzanne;Wang, Yunwei;Musch, Mark W.;Leone, Vanessa;Fehlner-Peach, Hannah;Nadimpalli, Anuradha;Antonopoulos, Dionysios A.;Jabri, Bana;Chang, Eugene B.
通讯作者: Chang, Eugene B.
DOI: 10.1126/science.1198469
发表时间: 2011-01-21
期刊: Science (New York, N.Y.)
影响因子: --
作者:
Atarashi K;Tanoue T;Shima T;Imaoka A;Kuwahara T;Momose Y;Cheng G;Yamasaki S;Saito T;Ohba Y;Taniguchi T;Takeda K;Hori S;Ivanov II;Umesaki Y;Itoh K;Honda K
通讯作者: Honda K
DOI: 10.1038/ajg.2013.257
发表时间: 2013-10-01
影响因子: 9.8
作者:
Angelberger, Sieglinde;Reinisch, Walter;Erry, David B.
通讯作者: Erry, David B.
DOI: 10.1038/nature08949
发表时间: 2010-04-29
期刊: Nature
影响因子: 64.8
作者:
通讯作者: --