Gangliosides as receptor modulators.
Gangliosides as receptor modulators.
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神经节苷脂作为受体调节剂。
DOI：
10.1007/978-1-4684-1200-0_32
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发表时间：
1984
影响因子：
--
通讯作者：
Hakomori,S
中科院分区：
文献类型：
--
作者：
Bremer,EG;Hakomori,S
A number of studies have postulated cell surface gangliosides to be receptors for various bioactive factors such as glycoprotein hormones,1–3interferon,4–6and bacterial toxins,7–9based on the interaction of gangliosides with these bioactive factors or ganglioside modification of the cellular effect of these factors. These observations, however, do not necessarily prove or support the idea that gangliosides function as receptors for these factors. In fact, in most of these cases, the receptor has been subsequently characterized as a protein, and the binding to gangliosides is generally of much lower affinity and specificity. With the exception of cholera toxin binding to the oligosaccharide moiety of GM1,10few examples of ganglioside receptors have been demonstrated. Our recent studies on the effect of gangliosides on cell growth have suggested that gangliosides may alter the binding of polypeptide growth factors to their receptors in an indirect way.
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DOI：
10.1016/0005-2760(78)90108-x
发表时间：
1978-01-01
期刊：
BIOCHIMICA ET BIOPHYSICA ACTA
影响因子：
--
作者：
SCHWARZMANN, G
通讯作者：
SCHWARZMANN, G
糖脂及其相关蛋白质：人红细胞表面成分交联的证据
影响因子：
3.5
作者：
C. Lingwood;S. Hakomori;T. Ji
通讯作者：
T. Ji
DOI：
10.1016/0006-291x(82)91769-7
发表时间：
1982-01-01
影响因子：
3.1
作者：
BREMER, EG;HAKOMORI, S
通讯作者：
HAKOMORI, S
干扰素与神经节苷脂的结合
影响因子：
64.8
作者：
F. Besançon;H. Ankel
通讯作者：
H. Ankel
加压素抑制表皮生长因子与培养的小鼠细胞的结合。
DOI：
10.1016/s0021-9258(19)70033-7
发表时间：
1981
期刊：
The Journal of biological chemistry
影响因子：
--
作者：
E. Rozengurt;K. Brown;P. Pettican
通讯作者：
P. Pettican