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Improving detection of disease genes involved in gene-gene and gene-environment interactions through joint modeling of the disease and a subphenotype

Improving detection of disease genes involved in gene-gene and gene-environment interactions through joint modeling of the disease and a subphenotype
通过疾病和亚表型的联合建模，改进参与基因-基因和基因-环境相互作用的疾病基因的检测
批准号：
200041
负责人：
Bureau Alexandre
金额：
$20.89万
依托单位：
Centre de recherche Universit Laval-Robert-Giffard (QC)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2010
资助国家：
加拿大
项目状态：
已结题
起止时间：
2010-03-01 至 2014-03-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=200041&lang=en
关键词：
Endophenotype Family-Based Association Analysis Gene-Gene Interaction Genetic Linkage Analysis Genetic Study Design Psychiatric Disorders

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中文摘要
翻译
大多数对健康有严重影响的疾病，如癌症、心血管疾病和精神疾病，都被称为复杂疾病，因为它们是由大量基因和环境因素联合收割机共同引起的。对于许多复杂的疾病，比较f
英文摘要
Most diseases with serious health impacts such as cancer, cardiovascular disease and psychiatric disorders are called complex due to the large number of genes and environmental factors that combine to cause them. For many complex diseases, comparing the f
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Predicting neurodevelopmental disorders from childhood trajectories of endophenotypes and genetic determinants in children born to an affected parent
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