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Role of the hypothalamo-pancreatic axis in the pathogenesis of type 2 diabetes

Role of the hypothalamo-pancreatic axis in the pathogenesis of type 2 diabetes
下丘脑-胰轴在2型糖尿病发病机制中的作用
批准号:
226247
负责人:
Alquier Thierry
金额:
$32.19万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2011
资助国家:
加拿大
项目状态:
已结题
起止时间:
2011-03-01 至 2015-03-01

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中文摘要
翻译
过量摄入高热量密度的营养素和肥胖会对周围和中枢胰岛素敏感组织(包括肌肉、肝脏和中枢神经系统(CNS))的胰岛素活动产生负面影响,这反过来又会促进2型糖尿病的发生
英文摘要
Excessive consumption of nutrients with high caloric density and obesity negatively affect insulin action in peripheral and central insulin-sensitive tissues including muscle, liver and the central nervous system (CNS) which in turn promote type 2 diabete
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会议论文
Central control of energy homeostasis by neuronal adipose triglyceride lipase
Gliopeptidic regulation of hypothalamic neuronal circuitry by endozepines and energy balance
Role of the hypothalamo-pancreatic axis in the pathogenesis of type 2 diabetes
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