Stereoselective Synthesis of Bioactive Alkaloids for Structure Elucidation and Drug Discovery

提出了开发具有生物活性的天然产物及其类似物的创新方法，这些天然产物及其类似物具有潜在的应用前景，可以作为新的和更安全的治疗药物和农用化学品。 这一项目将为推进合成有机化学的基本原理作出重要的科学贡献，并为澳大利亚作为知识型经济的发展作出贡献。 所开发的方法和产品很可能具有潜在的制药和农业应用，该国今后可从中受益。该项目将培训未来可能开发创新成果的技术人员，特别是在澳大利亚发展中的制药和生物技术行业。

It is proposed to develop innovative methods for preparing bioactive natural products and their analogues with potential applications as new and safer therapeutic drugs and agricultural chemicals. This project would make important scientific contributions to the advancement of the fundamentals of synthetic organic chemistry and contribute to Australia's development as a knowledge-based economy. The methodology and products developed are likely to have potential pharmaceutical and agricultural applications from which the country could benefit in the future. This project will train skilled people who may develop innovative outcomes in the future, especially in the developing pharmaceutical and biotechnology industries in Australia.