Specifically targeting CFTR activity as a therapeutic strategy to normalize cerebral blood flow in heart failure
Specifically targeting CFTR activity as a therapeutic strategy to normalize cerebral blood flow in heart failure
批准号:
355609
负责人:
Bolz Steffen S
金额:
$34.0万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2016
资助国家:
加拿大
项目状态:
已结题
起止时间:
2016-10-01 至 2019-10-01
中文摘要
血管通过改变其直径来控制血液流动。在大脑中,这一过程确保每个区域获得足够的血液来满足其新陈代谢需求。心脏病改变了血管控制其直径的方式,从而改变了血液流动。我们展示了
英文摘要
Blood vessels control blood flow by altering their diameter. In the brain, this process ensures that every region receives enough blood for its metabolic needs. Heart disease changes how blood vessels control their diameter and hence, blood flow. We show
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会议论文
Constitutive Smooth Muscle Tumor Necrosis Factor Regulates Microvascular Myogenic Responsiveness and Systemic Blood Pressure
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批准号:304953
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项目类别:Operating Grants
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资助金额:$19.21万
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财政年份:2014
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负责人:Bolz Steffen S
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依托单位:
Smooth muscle TNF/S1P signalling drives reduced cerebral perfusion in heart failure.
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批准号:237627
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项目类别:Operating Grants
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资助金额:$26.12万
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财政年份:2011
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负责人:Bolz Steffen S
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依托单位:
海外基金