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Understanding the neuro-immune: characterization of the epigenetic regulation by chromatin of the neuronal transcriptome underlying the expression of neuro-protective gene networks in response to chronic inflammatory insult in a mouse model of multiple sc

Understanding the neuro-immune: characterization of the epigenetic regulation by chromatin of the neuronal transcriptome underlying the expression of neuro-protective gene networks in response to chronic inflammatory insult in a mouse model of multiple sc
了解神经免疫:在多发性硬化症小鼠模型中,神经元转录组染色质的表观遗传调控是神经保护基因网络表达响应慢性炎症损伤的基础
批准号:
415862
负责人:
Drake Sienna S
金额:
$10.93万
依托单位:
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2019
资助国家:
加拿大
项目状态:
已结题
起止时间:
2019-11-01 至 2022-11-01

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中文摘要
翻译
尽管多发性硬化症的研究历史悠久,但科学家们仍然不清楚这种疾病的一些组成部分。神经退行性变与临床残疾最相关,但对神经退行性变背后的机制仍缺乏了解。这个
英文摘要
Despite the long history of MS research, some components of the disease continue to elude scientists. Neurodegeneration is the best correlate to clinical disability, but there remains a lack of understanding of the mechanisms behind neurodegeneration. The
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会议论文
Post-transcriptional regulation of gene expression in neuroinflammation
  • 批准号:
    386335
  • 项目类别:
    Studentship Programs
  • 资助金额:
    $1.27万
  • 财政年份:
    2017
  • 负责人:
    Drake Sienna S
  • 依托单位:
海外基金