Characterization of Stromal Cell Heterogeneity and Impact on Tumor Cell Drug Sensitivity in Non-small Cell Lung Cancer Treatment
Characterization of Stromal Cell Heterogeneity and Impact on Tumor Cell Drug Sensitivity in Non-small Cell Lung Cancer Treatment
批准号:
455148
负责人:
D'Arcangelo Elisa
金额:
$6.56万
依托单位国家:
加拿大
项目类别:
Fellowship Programs
财政年份:
2021
资助国家:
加拿大
项目状态:
已结题
起止时间:
2021-10-01 至 2023-10-01
中文摘要
肿瘤复发是晚期肺癌患者死亡的主要原因,是由于肿瘤细胞对治疗变得难治性。存在于肿瘤肿块内的基质细胞,如癌相关成纤维细胞(CAFs)和t细胞,在此过程中起着重要作用
英文摘要
Tumor recurrence is the main cause of death in late-stage lung cancer patients and is due to tumor cells becoming refractory to therapy. Stromal cells present within a tumor mass, such as cancer-associated fibroblasts (CAFs) and T-cells, play important ro
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