Unequal protein damage partitioning during asymmetric stem cell division determines the differential lifespan of progeny
Unequal protein damage partitioning during asymmetric stem cell division determines the differential lifespan of progeny
批准号:
197432
负责人:
Bufalino Mary R
金额:
$7.29万
依托单位:
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2009
资助国家:
加拿大
项目状态:
已结题
起止时间:
2009-11-01 至 2011-11-01
中文摘要
干细胞不对称分裂以自我更新并产生分化的细胞,例如皮肤细胞。虽然干细胞可以在生物体的整个生命过程中存活,但它们也容易受到衰老原因的影响,例如受损细胞的积累。
英文摘要
Stem cells divide asymmetrically to self-renew and produce a differentiated cell, for example a skin cell. Although stem cells can survive throughout the life of the organism they are also susceptible to causes of aging, such as the build up of damaged pr
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