Cell biological basis of a newly identified form of developmental and epileptic encephalopathy caused by variants in DENND5A, a guanine nucleotide exchange factor for Rab GTPases
Cell biological basis of a newly identified form of developmental and epileptic encephalopathy caused by variants in DENND5A, a guanine nucleotide exchange factor for Rab GTPases
批准号:
489016
负责人:
McPherson Peter S
金额:
$80.25万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2023
资助国家:
加拿大
项目状态:
未结题
起止时间:
2023-09-01 至 2028-09-01
中文摘要
神经系统的发育是一个非常复杂的过程。在大脑发育过程中,称为神经祖细胞的干细胞形式有两个作用,首先,它们需要增殖以确保大脑具有适当数量的细胞,
英文摘要
The development of the nervous system is a highly complex process. During brain development, forms of stem cells called neural progenitors have two roles, first, they need to proliferate to ensure that the brain has the appropriate number of cells, and se
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会议论文
The growing biomedical significance of intracellular membrane trafficking
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批准号:354042
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项目类别:Operating Grants
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资助金额:$213.36万
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财政年份:2016
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负责人:McPherson Peter S
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依托单位:
Altered membrane trafficking in neurological disease
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批准号:355751
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项目类别:Operating Grants
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资助金额:$53.78万
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财政年份:2016
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负责人:McPherson Peter S
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依托单位:
Regulating Rab-mediated membrane trafficking in cell physiology and disease
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批准号:266224
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项目类别:Operating Grants
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资助金额:$45.04万
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财政年份:2012
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负责人:McPherson Peter S
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依托单位:
Endosomal membrane trafficking in cell physiology and cancer
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批准号:238196
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项目类别:Operating Grants
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资助金额:$65.28万
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财政年份:2011
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负责人:McPherson Peter S
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依托单位:
Functional characterization of the machinery for clathrin-mediated endocytosis
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批准号:171099
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项目类别:Operating Grants
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资助金额:$48.0万
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财政年份:2008
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负责人:McPherson Peter S
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依托单位:
海外基金