Enhanced multivalent vaccine responses using a novel vaccine vector system

使用新型疫苗载体系统增强多价疫苗应答。该项目旨在开发一种多组分疫苗系统，以便在一次接种中对几种疾病靶标产生同等效力。新的和创新的疫苗设计策略，结合经济的商业生产过程，迫切需要新的和现有的人类和动物健康的应用。一种能够通过一次注射针对多种疾病的疫苗是加快未来疫苗开发和部署的一种明显方式。然而，接受者的免疫系统可以抑制对这些多组分疫苗的等效反应。该项目的研究有望解决这些问题，并为该疫苗平台的未来商业开发奠定基础。

Enhanced multivalent vaccine responses using a novel vaccine vector system. This project aims to develop a multicomponent vaccine system to deliver equal effectiveness against several disease targets in a single administration. New and innovative vaccine design strategies incorporating economical commercial production processes are urgently needed for new and existing human and animal health applications. A vaccine capable of targeting multiple diseases by a single injection is an obvious way to expedite future vaccine development and deployment. However, the recipient’s immune system can repress equivalent responses to these multicomponent vaccines. This project’s research is expected to address these problems, and underpin the future commercial development of this vaccine platform.