Reductive Biological Transformation of Alkyl Halides

烷基卤化物是美国最普遍的地下水污染物，也是危险废物的重要组成部分。这些化合物的生物转化潜力直到最近才被发现。原位生物转化似乎是净化地下水中这些污染物的极好可能性，但显然需要更好地了解微生物和环境因素。利用生物过程处理危险废物也具有良好的潜力。将研究影响烷基卤化物和中间体生物转化速率的环境因素，这些中间体是用观察到的产生转化的微生物的纯培养物形成的。环境因素包括氧化还原环境、温度、电子供体和受体以及微生物种类。

Alkyl halides are the most prevalent groundwater contaminants in the United States and are significant components of hazardous wastes. The potential for biological transformation of these compounds has been found only recently. In-situ biotransformation appears an excellent possibility for cleansing groundwaters of these contaminants, but a better understanding of the microorganisms and environmental factors is clearly needed. Good potential also exists for use of biological processes for treatment of hazardous wastes. Studies will be conducted on environmental factors affecting rates of biotransformation of alkyl halides and intermediates formed using pure cultures of microorganisms observed to bring about the transformations. Environmental factors of interest are redox environment, temperature, electron donors and acceptors, and microbial species.