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Dissecting the roles of DNA-binding autoinhibition, post-translational modification and protein partnerships in the regulation of the transcription factor ETV6 (or TEL)

Dissecting the roles of DNA-binding autoinhibition, post-translational modification and protein partnerships in the regulation of the transcription factor ETV6 (or TEL)
剖析 DNA 结合自抑制、翻译后修饰和蛋白质伙伴关系在转录因子 ETV6(或 TEL)调节中的作用
批准号:
300387
负责人:
De Soumya
金额:
$6.01万
依托单位国家:
加拿大
项目类别:
Fellowship Programs
财政年份:
2013
资助国家:
加拿大
项目状态:
已结题
起止时间:
2013-11-01 至 2015-09-01

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中文摘要
翻译
白血病是一种影响血液和骨髓的癌症。蛋白质ETV6广泛涉及各种形式的白血病,并且是重要的治疗靶点。ETV6是一种转录因子,在血液形成中起关键作用
英文摘要
Leukemia is a type of cancer that affects blood and bone marrow. The protein ETV6 has been widely implicated in various forms of leukemia and is an important therapeutic target. ETV6 is a transcription factor that plays key roles in the formation of blood
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