The infectome of NSW dairy calves, a genomic microbial surveillance

传染病是犊牛患病和死亡的主要原因。对新南威尔士州奶牛传染性致病菌多样性的了解并不全面。因此，本提案的直接目标是利用非靶向微生物基因组测序来纠正这一知识差距，以表征和识别奶牛中已知的和新出现的肠道和呼吸道病原体。我们将确定其微生物物种在所有新南威尔士州乳制品地区的发生和分布。这将使澳大利亚乳业能够改善动物健康和生产力，提高诊断能力，从而使农民能够就疾病控制战略作出知情的管理决策。

Infectious diseases are the main cause of disease and mortality in calves. The knowledge of the diversity of infectious disease-causing agents in NSW dairy cattle is not comprehensive. Thus, the immediate goal of this proposal is to redress this knowledge gap using untargeted microbial genomic sequencing to characterise and identify known and emerging enteric and respiratory pathogens in dairy calves. We will determine the occurrence and distribution of their microbial species across all NSW dairy regions. This will enable the Australian dairy industry to improve animal health and productivity, and diagnostic capacity, which will allow farmers to make informed management decisions about disease control strategies.