Improved biosecurity through the engineering of microbial ecosystems

通过微生物生态系统工程改善生物安全

• 批准号: LP150100912
• 负责人: Prof Steven Djordjevic
• 金额: $ 36.17万
• 依托单位: University of Technology Sydney
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Projects
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-03-01 至 2020-04-30
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LP150100912
• 关键词: Improved; biosecurity; through; engineering; microbial

This project aims to provide data and understanding that will help develop predictive models for changes in the distribution of drug-resistant bacteria, and surveillance and response programs for key biosecurity threats. Microorganisms, including commensals and pathogens, can live in complex communities in a range of environments including animal hosts. It is now known that these communities (known as microbiomes) can exert a profound effect on animal health. This project seeks to understand where antimicrobial resistance genes reside in pig gut microbiotia and how they move between members of this complex microbial community, and to provide information on how probiotics may be used to reduce dependence on antibiotics.

该项目旨在提供数据和理解，以帮助开发耐药细菌分布变化的预测模型，以及针对关键生物安全威胁的监测和应对计划。微生物，包括细菌和病原体，可以在包括动物宿主在内的一系列环境中以复杂的群落生活。现在人们知道，这些群落（称为微生物组）可以对动物健康产生深远的影响。该项目旨在了解抗菌素耐药性基因在猪肠微生物群中的位置以及它们如何在这个复杂的微生物群落成员之间移动，并提供有关益生菌如何用于减少对抗生素依赖的信息。