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Development of Living Neuronal Transducers for Biochemical Sensing

Development of Living Neuronal Transducers for Biochemical Sensing
用于生化传感的活体神经元传感器的开发
批准号:
8609910
负责人:
Bernard Van Wie
金额:
$3.0万
依托单位:
依托单位国家:
美国
项目类别:
Standard Grant
财政年份:
1986
资助国家:
美国
项目状态:
已结题
起止时间:
1986-06-15 至 1987-11-30

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中文摘要
翻译
本研究的目的是评估在生物技术过程中使用活神经元的新型传感器的潜力。神经元将负责检测化学物质(如脂肪族碳氢化合物,如低分子量醇、酮、醛和羧酸),并将电信号传递到合适的测量设备(如微电极或场效应传感器)。这种类型的传感器预计对小浓度的目标物质非常敏感,并且应该允许立即和重复进行测量。
英文摘要
The objective of this research is to assess the potential for using living neurons in a new type of sensor for biotechnological processes. The neurons will be responsible for both the detection of chemical substances (i.e., aliphatic hydrocarbons like low molecular weight alcohols, ketones, aldehydes, and carboxylic acids) and the relaying of an electrical signal to a suitable measuring device (such as a microelectrode or field effect transducer). Sensors of this type are expected to be extrememly sensitive to small concentrations of target substances and should allow measurements to be made instantly and repeatedly.
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