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Further Characterization of the Dolutegravir Resistance Mutation R263K: Combinations with Primary INSTI Resistance Mutations and Possible Compensatory Mechanisms

Further Characterization of the Dolutegravir Resistance Mutation R263K: Combinations with Primary INSTI Resistance Mutations and Possible Compensatory Mechanisms
多替拉韦耐药突变 R263K 的进一步表征:与主要 INSTI 耐药突变和可能的补偿机制的组合
批准号:
311953
负责人:
Anstett Kaitlin
金额:
$1.27万
依托单位:
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2013
资助国家:
加拿大
项目状态:
已结题
起止时间:
2013-12-01 至 2014-12-01

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中文摘要
翻译
据估计,目前全世界有3 400多万人感染了人体免疫缺陷病毒(艾滋病毒)。虽然抗逆转录病毒疗法挽救了许多艾滋病毒阳性者的生命,但耐药性威胁到其长期疗效。
英文摘要
It is estimated that over 34 million people are currently infected with human immunodeficiency virus (HIV) worldwide. Although antiretroviral therapy has been lifesaving for many HIV-positive individuals, drug resistance threatens its long-term efficacy.
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会议论文
Investigation of the sequential development of integrase strand transfer inhibitor resistance mutations in HIV.
  • 批准号:
    324345
  • 项目类别:
  • 资助金额:
    $0.11万
  • 财政年份:
    2015
  • 负责人:
    Anstett Kaitlin
  • 依托单位:
The Modulation of R263K-Mediated HIV-1 Resistance to Integrase Strand Transfer Inhibitors by Acetylation.
  • 批准号:
    347939
  • 项目类别:
    Studentship Programs
  • 资助金额:
    $7.65万
  • 财政年份:
    2015
  • 负责人:
    Anstett Kaitlin
  • 依托单位:
Characterization of Dolutegravir Resistance Mutation R263K by Combination with Primary INSTI Resistance Mutations
  • 批准号:
    311375
  • 项目类别:
  • 资助金额:
    $0.11万
  • 财政年份:
    2014
  • 负责人:
    Anstett Kaitlin
  • 依托单位:
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