Distribution and Biosynthesis of Plant Lectins

植物凝集素的分布和生物合成这项拟议中的研究扩展了埃兹勒博士关于豆科植物扁豆凝集素蛋白家族的生物合成、分布和调控的工作，这些凝集素蛋白最近被确定了特征。它解决了这样的问题，即导致这些蛋白质不同亚细胞分布的生物合成步骤是什么，以及生物合成是如何调节的。凝集素是一种蛋白质，最初在植物中发现，它以高度特异的方式结合某些糖基。凝集素的生理作用(S)尚不清楚，但它们的广泛出现暗示了它们的重要性。有人认为，它们可以作为识别分子。这项研究的结果将有助于最终理解植物凝集素的生理作用，并为密切相关蛋白质的产生的时空调控提供基本信息。

Distribution and Biosynthesis of Plant Lectins. The proposed research extends Dr. Etzler's work on the biosynthesis, distribution and regulation of a family of lectin proteins from the legume, Dolichos biflorus that have recently been characterized. It addresses such questions as what are the biosynthetic steps leading to the different subcellular distributions of these proteins and how is the biosynthesis regulated. Lectins are proteins, originally identified in plants, that bind certain sugar moieties in a highly specific manner. The physiological role(s) of lectins is still unknown but their widespread occurrence implies their importance. It has been suggested that they act as recognition molecules. The results of this study should contribute to an eventual understanding of the physiological role of plant lectins as well as provide basic information on the spatial and temporal regulation of the production of closely related proteins.