Phase Behavior of Supercritical Fluid Mixtures for use in Electroorganic Synthesis

该项目的目标是确定在超临界流体中进行电有机反应的可行性。二甲基甲酰胺的合成、Kolbe反应和以硝基苯为原料合成对氨基苯酚已被确定为合适的候选反应。该项目的初步研究将集中在反应体系的溶剂混合物的相行为上。在随后的电化学研究中，将测定溶液电导率、表面过电位和反应选择性。目标是确定溶剂、电极材料和操作条件的组合，在这些条件下可以有效地执行反应。在超临界区域操作可能导致强化传质、增加选择性、增加反应物的溶解度和改善产品分离。

It is the goal of the project to determine the feasibility of performing electroorganic reactions in supercritical fluids. The synthesis of dimethylformamide, a Kolbe reaction, and the synthesis of p-aminophenol, from nitrobenzene, have been identified as suitable candidate reactions. Initial studies in this project will focus on the phase behavior of the solvent mixtures of the reacting systems. In subsequent electrochemical studies, solution conductivity, surface overpotential, and reaction selectivity will be determined. The goal is to identify combinations of solvents, electrode materials, and operating conditions where the reactions can be efficiently performed. Operation in the supercritical region may lead to enhanced mass transport, increased selectivity, increased reactant solubility, and improved product separation.