Eukaryotic Chromosome Replication Conference, Cold Spring Harbor, NY, September 2-6, 1987

这是一项部分支持将于1987年9月举行的4天真核染色体复制会议的建议，这是在冷泉港实验室举行的关于癌症的年度系列研讨会的一部分。将涵盖的主题包括：病毒基因组复制、染色体复制和基因扩增、复制蛋白、端粒和着丝粒的结构和功能、细胞周期进程的控制以及相关主题。斯蒂尔曼博士和凯利博士因在体外复制SV40和腺病毒DNA方面的开创性研究而闻名。他们建议召开一次会议，涵盖DNA复制(体内和体外)、染色体结构和染色体中特定基因拷贝数调节(基因放大)等领域的广泛基础研究。这些都是当前许多研究人员感兴趣的重要问题。冷泉港实验室提供了一个高效但非正式的环境，鼓励人们进行讨论。会议应该是及时和成功的。

This is a proposal for partial support of a 4 day meeting on Eukaryotic Chromosome Replication to be held in September, 1987 as part of an annual series of symposia on cancer at the Cold Spring Harbor Laboratory. The topics to be covered include: replication of viral genomes, chromosome replication and gene amplification, replication proteins, structure and function of telomeres and centomeres, control of cell cycle progression, and related subjects. Drs. Stillman and Kelly are well known for pioneering studies of the in vitro replication of SV40 and adenovirus DNAs. They propose to hold a conference which will cover a wide variety of basic research in the areas of DNA replication (in vivo and in vitro), chromosome structure, and the regulation of the number of copies of particular genes that are in the chromosome (gene amplification). These are important problems of current interest to many investigators. The Cold Spring Harbor Laboratory provides an efficient but informal environment that stimulates discussion. The meeting should be timely and successful.