Marked cardiac dysfunction and mortality associated with cardiac specific deletion of JAK2
Marked cardiac dysfunction and mortality associated with cardiac specific deletion of JAK2
批准号:
306378
负责人:
Karmazyn Morris
金额:
$49.99万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2014
资助国家:
加拿大
项目状态:
已结题
起止时间:
2014-03-01 至 2019-03-01
中文摘要
Janus kinase2(JAK2)是一种存在于包括心脏在内的许多组织中的酶,但其功能,特别是在心脏病方面的功能尚不清楚。从严重心力衰竭患者身上取出的心脏显示出JAK2活性抑制。虽然是间接的
英文摘要
Janus kinase 2 (JAK2) is an enzyme found in many tissues including the heart although its function especially with respect to heart disease is not known. Hearts removed from patients with severe heart failure show depressed JAK2 activity. While indirect
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