The Contribution of Leptin to Myocardial Hypertrophy, Remodelling and Failure: Mechanisms and Studies Into Leptin-Adiponectin Interactions

瘦素对心肌肥厚、重构和衰竭的作用：瘦素-脂联素相互作用的机制和研究

• 批准号: 266232
• 负责人: Karmazyn Morris
• 金额: $ 51.57万
• 依托单位: University of Western Ontario
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2012
• 资助国家: 加拿大
• 起止时间: 2012-09-01 至 2017-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=266232&lang=en
• 关键词: Adiponectin; Cell Signalling; Heart Failure; Hypertrophy; Leptin; Mitochondria; Sex Differences

Leptin (derived from the Greek word Leptos which means thin) is a small protein synthesized primarily from fat cells called adipocytes. Leptin levels in the blood are generally quite low but are greatly increased in obesity. Although the major function

瘦素（来源于希腊语Leptos，意思是瘦）是一种主要由脂肪细胞合成的小蛋白质。血液中的瘦素水平通常很低，但肥胖会大大增加。虽然主要功能