Acquisition of an AM 400 Spectrometer

核磁共振波谱（NMR）已成为有机化学和生物有机化学的主要分析工具，在无机化学和生物物理化学中也具有重要意义。购置这种精密仪器大大提高了一个部门进行一线研究的能力。二维核磁共振（COSEY和NOESY技术等）的最新进展极大地增强了它在这些领域的应用，尽管这样的实验非常耗时。该合同与美国国立卫生研究院的仪器合同相结合，将能够获得一台400 MHz核磁共振光谱仪，能够进行二维光谱和其他需要最先进设备和大量时间的技术。该仪器还将补充该部目前的能力，并最大限度地利用现有设施的总体效用。参与有机金属化学、有机合成、生物有机合成和生物有机机制研究的项目将通过获得该仪器而得到加强。

Nuclear magnetic resonance spectroscopy (NMR) has become the primary analytical tool in organic and bioorganic chemistry, and of major importance in inorganic and biophysical chemistry as well. Acquisition of such sophisticated instrumentation greatly increases the ability of a department to carry out front line research. Recent advances in two-dimensional (2-D) NMR (COSEY and NOESY techniques, etc.) have dramatically enhanced its application in these fields, in spite of the fact that such experiments are very time-consuming. This award, when coupled with an instrumentation award from NIH, will enable the acquisition of a 400 MHz NMR spectrometer capable of carrying out 2-D spectroscopy and other techniques requiring state-of-the-art equipment and large blocks of time. The instrument will also complement the present capabilities of the department and maximize the overall utility of the present facility. Programs involved in studies of organometallic chemistry, organic synthesis, biorganic synthesis and bioorganic mechanisms will be enhanced by acquisition of the instrument.