Conformational Analysis of Polysaccharides

多糖是最大类的天然存在的物质之一。 它们存在于每一种生命形式中，表现出复杂的结构， 与广泛的生物功能有关。 他们的研究是 为了了解它们的结构、功能和生物学特性， 功能协调发展的 这些目标可以通过表征 构象，晶体和形态结构特征，这些 物质. Sarko博士将使用衍射分析，主要是X级和电子 在这个项目中， 这些方法将由计算机辅助- 基于模型分析。 这样做的目的是增加可靠性 结构分析的重要性，并使结构预测成为可能。 的 建模技术将涉及分子和量子方法 力学和分子动力学。

Polysaccharides are one of the largest classes of naturally occurring substances. They are found in every form of life where they exhibit complex structures and are associated with a wide range of biological functions. Their study is important in order to understand their structures, popoerties and biological functions. These goals can be achieved by the characterization of conformational, crystalline and morphological structural features of these substances. Dr. Sarko will use diffraction analysis, primarily X-rated and electron diffraction in this project. These methods will be complemented by computer- based model analysis. The purpose for this is both to increase the reliability of structural analysis and to make prediction of structure possible. The modeling techniques to be used will involve the methods of molecular and quantum mechanics and molecular dynamics.