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The Classification of Prokaryotes

The Classification of Prokaryotes
原核生物的分类
批准号:
8705352
负责人:
Carl Woese
金额:
$21.45万
依托单位国家:
美国
项目类别:
Continuing Grant
财政年份:
1987
资助国家:
美国
项目状态:
已结题
起止时间:
1987-10-15 至 1991-03-31

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中文摘要
翻译
伊利诺伊大学的卡尔·沃斯博士将继续 他对理解自然(系统发育) 无数真细菌之间的关系 的 物种之间的进化关系是通过 确定之间的相似度(或差异) 从一个物种到另一个物种的核糖体RNA序列。 从一组 (二进制)序列差异-表示为百分比 序列差异,或根据实际核苷酸 序列中显示差异的位置-进化 树可以通过标准的统计程序构建, 第一种情况是通过所谓的距离矩阵分析, 第二种方法称为最大简约分析法。 核糖体RNA是一个关键的和高度保守的分子, 细胞参与翻译过程, 遗传信息被“翻译”成酶, proteins. 因此,它在其序列比对中保留了 大量的历史信息, 血统 沃斯博士是分子生物学的先驱 细菌基因系统发育分析方法 细菌进化
英文摘要
Dr. Carl Woese of the University of Illinois will continue his work toward understanding the natural (phylogenetic) relationships among the myriad species of eubacteria. The evolutionary relationships among species are assessed by determining the degree of similarity (or difference) between ribosomal RNA sequences from one species to another. From a set of (binary) sequence differences - expressed either as percent sequence difference, or in terms of the actual nucleotide positions in the sequence that show differences - evolutionary trees can be constructed by standard statistical procedures, in the first case by what is called distance matrix analysis, in the second by the procedure known as maximum parsimony analysis. Ribosomal RNA is a key and highly conserved molecule in the cell, being involved in the translation process, the process whereby genetic information is "translated" into enzymes and proteins. Therefore, it has retained in its sequence alignment a significant amount of historical information about various lineages. Dr. Woese has pioneered the development of molecular methods for phylogenetic analysis of bacterial genes and of bacterial evolution.
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RDP: Ribosomal Database Project
The Classification of Prokaryotes
The Classification of Prokaryotes
Interactive Ribosomal RNA Database
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