Activity of Premotor Cortex Neurons During Two Dimensional Movements

前运动皮层是大脑皮层的主要区域之一， 大脑皮层被认为参与了许多方面 运动行为。 一种观点是，它在 学习运动技能。 病变研究表明， 根据记忆回忆动作。 其他研究表明， 这部分皮层参与运动准备。 Timothy Ebner博士认为这个大脑区域与 肢体或手的准备和视觉引导 在自愿运动到可到达的各个区域期间， 额外的私人空间。 他的工作就是在这个假设下进行的。 在灵长类动物中， 这需要在视觉上引导光标进入水平平面 靶区，运动前区单个神经元的放电 将记录皮质。 细胞活动的四个方面 与复杂运动的关系。 第一， 定义二维空间内的区域，在该区域中 在到达运动期间调制。 第二，关系 前运动皮层神经元的放电模式和 将解决运动学问题。 第三，响应性 前运动皮层神经元的“错误”在运动性能， 将对纠正措施进行评估。 四、如何放电 在适应运动的过程中， 匹配外部暴露的约束将被确定。 总的来说，这些研究将确定两个 三维的，视觉引导的运动被表示在 前运动皮层

The premotor cortex, one of the major areas of the cerebral cortex is suggested to be involved in numerous aspects of motor behavior. One idea is that it has a role in the learning of motor skills. Lesions studies suggest deficits in recalling movements from memory. Other studies show the involvement of this part of the cortex in movement preparation. Dr. Timothy Ebner believes this brain area is concerned with the preparation and visual guidance of the limbs or hands during voluntary movements into various regions of reachable extra personal space. His work proceeds under that hypothesis. In primates trained to make voluntary movements in the horizontal plane which require visually guiding a cursor into target zones, the discharge of single neurons in the premotor cortex will be recorded. Four aspects of the cell's activity in relation to complex movements will be studied. First, is to define the region within two dimensional space in which a cell is modulated during reaching movements. Second, the relationship between the discharge pattern of premotor cortical neurons and movement kinematics will be addressed. Third, the responsiveness of premotor cortex neurons to "errors" in motor performance and corrective movement will be evaluated. Fourth, how the discharge of single cells change in the process of adapting a movement to match externally exposed constraints will be determined. Overall, these studies will define which features of two dimensional, visually guided movements are represented in the premotor cortex.