U.S.-France Cooperative Research: Electron Crystallography of Plant Polysaccharides

该奖项将支持合作研究， 克莱姆森大学的唐纳德米勒教授和H. Chanzy of the Centre de Recherche sur les 法国格勒诺布尔CNRS的植物大分子， 在有机物的分子成像领域， 材料. 这些材料很容易被破坏， 用于无机物成像的电子束 材料. 因此，特殊的成像技术必须 开发，利用低能量束， 牺牲分辨率。 这项工作的目的是 以提高分辨率， 植物电子束分子图像 可以得到多糖。 电子束图像 将产生，使用电子显微镜在 法国合作机构;图像将 使用图像处理算法进行增强 由美国调查员开发。 激光 干涉测量法将用于获得平行数据， 分子结构来检查算法 开发 两个实验室的能力， 调查人员是互补的，有设备， 电子束成像的专业知识已经具备 和美国的图像处理技术。 在法国开发的技术将是 转移到美国实验室， 可供美国研究者以后使用， 他对植物聚合物的研究 这些技术将 也可用于其他束敏感的研究 材料，如病毒样品或聚合物 光刻胶。

This award will support collaborative research between Prof. Donald Miller of Clemson University and Dr. H. Chanzy of the Centre de Recherche sur les Macromolecules Vegetales, of CNRS in Grenoble, France, in the area of molecular imaging of organic materials. These materials are easily destroyed by the electron beams used in imaging inorganic materials. Therefore, special imaging techniques must be developed, which utilize low-energy beams without sacrificing resolution. The objective of this work is to increase the resolution with which electron-beam-derived molecular images of plant polysaccharides can be obtained. Electron-beam images will be produced, using the electron microscope at the collaborating French institution; the images will then be enhanced, using image-processing algorithms developed by the U.S. investigator. Laser interferometry will be used to obtain parallel data on molecular structure in order to check the algorithms developed. The capabilities of the two laboratories and investigators are complementary, with equipment and expertise for electron-beam imaging already available in France and image-processing expertise in the U.S. The techniques to be developed in France will be transferred to the U.S. laboratory, where they will be available for later use by the U.S. investigator in his studies of plant polymers. These techniques will also be useful for the study of other beam-sensitive materials, such as viral samples or polymeric photoresists.