Metal Vinylidenes and Carbenes in Synthetic Organic Chemistry

有机合成计划是支持教授的工作。 西北大学的安东尼·巴雷特。 巴雷特教授是 研究金属如何与碳、有机金属 化合物，可以提供独特的方法， 结构复杂的分子。 该项目将研究 这些有机金属化合物如何反应的细节，以及 其使用的局限性。 将特别关注 制备化学环化合物的方法。 含环 化合物是自然界中常见的，其中一个重要的 有机化学家的使命是寻找新的方法来建立， 在实验室里，可以在 自然 阳离子铁粉的应用！亚乙烯基试剂 构建多种杂环和碳环 分子将被研究。 反应会集中在 杂环和碳环的新型环化方法 环. 该研究将探讨以下基本问题： 有机金属试剂的反应模式。 为 新开发技术的范围变得众所周知， 方法将应用于设计有效的路线， 合成有机化学家感兴趣的分子骨架。

The Organic Synthesis Program is supporting the work of Prof. Anthony Barrett of Northwestern University. Prof. Barrett is studying how metals connected to carbon, organometallic compounds, can provide unique methods for preparing structurally complex molecules. The project will study the details of how these organometallic compounds react, and the limitations of their use. Special attention will focus on methods for making chemical ring compounds. Ring-containing compounds are common to Nature, and one of the important missions of organic chemists is to find new ways to build, in the laboratory, the kinds of compounds that can be found in Nature. The application of cationic ironıII! vinylidene reagents to the construction of a diversity of heterocyclic and carbocyclic molecules will be investigated. The reactions will be focused on novel cyclization approaches to heterocyclic and carbocyclic rings. The research will explore the fundamental questions of the mode of reactivity of the organometallic reagents. As the scope of the newly-developing technology becomes known, the methods will be applied to designing efficient routes to molecular skeletons of interest to synthetic organic chemists.