Purchase of an ORD/CD Spectropolarimeter

化学家研究了圆二色性（CD）和旋光色散（ORD）现象，以获得对具有手性的分子内原子的特殊排列的特殊认识。当一个分子不能与其镜像重叠时，就称为手性分子。用于研究这种现象的关键仪器是CD/ORD分光偏振仪。对于那些从事涉及手性分子的现代研究的化学家来说，使用该仪器是必不可少的。这份来自化学共享仪器项目的合同将帮助密苏里大学圣路易斯分校的化学系获得一台CD/ORD分光偏振仪。此次收购将加强的化学研究领域包括：1)高对称性水系镧系配合物的结构与光谱研究2)有机-氘化合物的圆二色性研究3)手性硫芳基烯的合成与结构研究4)脱铁过程构象变化检测5)人工酶的底物取向和活性位点。

The phenomena of Circular Dichroism (CD) and Optical Rotatory Dispersion (ORD) are studied by chemists in order to gain special insight into the specific arrangement of atoms within molecules that possess the property of chirality. A molecule is said to be chiral when it is not superimposable on its mirror image. A crucial instrument used to study the phenomena is the CD/ORD spectropolarimeter. Access to the instrument is essential to those chemists carrying out modern research involving chiral molecules. This award from the Chemistry Shared Instrumentation Program will help the Department of Chemistry at the University of Missouri at St. Louis to acquire a CD/ORD spectropolarimeter. The areas of chemical research that will be enhanced by the acquisition include the following: 1) Structure and spectroscopy of high-symmetry aqueous lanthanide complexes 2) Circular dichroism of organo-deuterium compounds 3) Synthesis and structure of chiral thioaryl allenes 4) Detecting conformational changes during iron removal from transferrin 5) Orientation of substrates and active sites in artificial enzymes.