Presidential Young Investigator Award

PI的研究兴趣是应用免疫学， 生物分离、人造器官和蛋白质科学， 工程. 在应用免疫学领域，他对 各种现象与应用的重要问题， 生物技术和医学。 这些研究包括：（1） 抗原-抗体复合物结构和动力学 与各种血液传播分子和细胞的相互作用，（2） 利用光激活药物开发新的靶向疗法， （3）淋巴细胞活化的动力学研究 淋巴因子 在人造器官领域，PI目前 研究涉及人工肝和人工肝的开发。 通过用半渗透性材料包封胰腺或肝细胞 膜。 在生物分离领域，几种新方法 正在研究的包括：（1）亲和层析 利用电场和高压进行分离，（2）开发 亲和反胶团，（3）电 可控聚电解质膜技术。 等领域 蛋白质科学与工程，PI的研究兴趣在于 定义有助于蛋白质稳定性的现象， 不同的环境。

The PI's research interests are in the fields of applied immunology, bioseparations, artificial organs, and protein science and engineering. In the area of applied immunology, he has an interest in a variety of phenomena with application to important issues in biotechnology and medicine. These include: (1) studies on the structure and dynamics of antigen-antibody complexes and their interaction with various blood-borne molecules and cells, (2) development of novel targeting therapies with light-activatable drugs, and (3) studies of the dynamics of activation of lymphoid cells by lymphokines. In the area of artificial organs, the PI's current research involves development of an artificial liver and an artificial pancreas by encapsulating pancreatic or liver cells with semipermeable membranes. In the field of bioseparations, several; new approaches are under investigation including: (1) affinity chromatographic separations using electric fields and high pressure, (2) development of affinity reversed micelles, and (3) development of electrically controlled polyelectrolyte membrane technology. In the fields of protein science and engineering, the PI's research interests lie in defining the phenomena that contribute to protein stability in different environments.