Hormonal Regulation of Lipid Metabolism in Fish

在这项研究中，激素对脂质（脂肪）的作用和相互作用 将研究肝脏中的代谢，特别是脂质代谢。 肝脏是动物代谢的重要器官， 存在关于其作为脂肪储存的作用的信息。 鱼（奇努克 鲑鱼，虹鳟鱼），它们具有独特的储存脂质的能力， 他们的肝脏是这些研究的模型。 初步调查将集中在各种胰腺炎的行动， 激素（胰岛素、胰高血糖素和生长抑素）。 的 特定激素的代谢作用以及 这种激素与其他激素的混合物将被检测。 的关系 脂质代谢和碳水化合物改变之间的关系 代谢以及生物化学过程中运作的 将检查肝细胞以确定 胰腺激素影响脂质代谢。

In this study the action and interaction of hormones on lipid (fat) metabolism, particularly lipid metabolism in liver will be investigated. The liver is an important organ in animal metabolism, however, little information exists concerning its role as a fat store. Fish (chinook salmon, rainbow trout), which have a unique ability to store lipid in their liver, are the model for these studies. Initial investigations will focus on the actions of various pancreatic hormones (insulin, glucagon and somatostatin) in the whole animal. The metabolic action of a particular hormone as well as the interaction of that hormone with other hormones will be examined. The relationship between aspects of lipid metabolism and alteration in carbohydrate metabolism as well as the biochemical processes operating within the liver cell will be examined to determine the mechanisms by which pancreatic hormones influence lipid metabolism.