Rational design of array-based nanozyme sensors

该项目旨在深入了解纳米生物界面上的分子相互作用，并利用这些知识开发一种强大的传感器技术，用于快速检测复杂样品中的食源性病原体。该项目建议采用一种模仿嗅觉和味觉的创新方法，在这种方法中，一系列适体有望协同工作，以精确识别目标，从而提供优于当前传感技术的优势。预期的结果包括一个现成的用于检测食品污染物的分析工具。这将通过支持澳大利亚食品和卫生部门以及传感器技术的潜在商业化，提供重大的经济、卫生和社会效益。

The project aims to obtain a deep understanding of molecular interactions at the nano-bio interface, and use this knowledge to develop a robust sensor technology for the rapid detection of foodborne pathogens in complex samples. The project proposes to employ an innovative approach that mimics the senses of smell and taste, where an array of aptamers are expected to work in synergy to precisely identify a target, providing an edge over current sensing technologies. Expected outcomes include a ready-to-go analytical tool for the detection of food contaminants. This should provide significant economic, health, and social benefits through supporting Australian food and health sectors, and the potential commercialisation of sensor technologies.