Discovery and characterization of alternative splicing regulatory networks with critical roles in development and disease
Discovery and characterization of alternative splicing regulatory networks with critical roles in development and disease
批准号:
333820
负责人:
Blencowe Benjamin J
金额:
$482.8万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2015
资助国家:
加拿大
项目状态:
已结题
起止时间:
2015-09-01 至 2022-09-01
中文摘要
我们已经证明,几乎所有的人类基因通过一个被称为选择性剪接的过程编码多种蛋白质产物。每个基因被转录成包含编码和非编码片段的RNA拷贝。RNA剪接将编码片段连接成
英文摘要
We have shown that almost all human genes encode multiple protein products through a process known as alternative splicing. Each gene is transcribed into an RNA copy that contains coding and non-coding segments. RNA splicing joins the coding segments into
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海外基金