Convergence of Frontal Eye Field and Medial Cerebellar Nucleus (Fastigial) Projections in Brainstem Preoculomotor Nuclei

我们知道大脑中控制眼球运动的几个区域，但我们对它们在哪里相互联系以使眼睛以协调和反应的方式移动知之甚少。为了研究这种相互联系，将在大脑的两个部位注射两种不同的神经解剖学示踪剂。这项实验将测试大脑皮层前部眼场是否与小脑顶核投射的细胞相连。电子显微镜将被用来证明识别出的轴突是否终止在同一个神经元上，如果是的话，突触关系是什么。这项研究应该会增加我们对眼球运动如何以及在哪里进行控制的了解。

We know several of the areas in the brain which control eye movement but we know little about where they are inter connected for the eyes to move in a coordinated and responsive fashion. To study one such interconnection two sites in the brain will be injected with two different neuroanatomical tracers. The experiment will test if the cortical frontal eye field is connected to the same cells as the cerebellar fastigial nucleus projections. Electron microscopy will be used to prove if the identified axons terminate on the same neuron and if so what the synaptic relationships are. The study should increase our knowledge of how and where eye movement is controlled.