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Modulation of UV damage repair by replicative stress-induced RPA exhaustion during skin cancer development

Modulation of UV damage repair by replicative stress-induced RPA exhaustion during skin cancer development
皮肤癌发展过程中复制应激诱导的 RPA 耗竭对紫外线损伤修复的调节
批准号：
368659
负责人：
Wurtele Hugo
金额：
$57.68万
依托单位：
Centre de recherche de l'Hôpital Maisonneuve-Rosemont (Montral)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2017
资助国家：
加拿大
项目状态：
已结题
起止时间：
2017-09-01 至 2022-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=368659&lang=en
关键词：
Dna Repair Dna Replication Genetic Determinants Of Cancer Melanoma Mutagenesis Nucleotide Excision Repair

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中文摘要
翻译
皮肤癌是高加索人群中最常见的肿瘤。大多数皮肤癌是非黑色素瘤，很少扩散，不会危及生命。相比之下，除非迅速切除，否则恶性黑色素瘤的扩散速度极快
英文摘要
Skin cancer is the most frequent tumour in Caucasian populations. A majority of skin cancers is of the nonmelanoma variety, which rarely spread and are not life threatening. In contrast, unless promptly removed, malignant melanoma spreads extremely rapidl
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